RED LIGHT INFO

Summary of Reverse skin aging signs by red light photobiomodulation

Couturaud, Le Fur, Pelletier, and Granotier (2023) present a clinical study investigating whether red light photobiomodulation (via a LED mask) can reverse visible signs of skin aging. PubMed Central

Background & Rationale

•   Photobiomodulation (PBM) is a process in which cells absorb red or near-infrared light, leading to enhanced mitochondrial activity, elevated ATP production, modulated reactive oxygen species, and stimulated cell signaling and growth factor expression. PubMed Central+1

•   In dermatological use, low-level red light (600–700 nm) penetrates into the dermis and is known to stimulate collagen and elastin production, reduce oxidative stress, and thereby act against aging changes like wrinkles, loss of firmness, and reduced skin density. PubMed Central+2PubMed Central+2

Methods

•   The study used a Skin Light Dior × Lucibel mask, emitting cold red light at ~630 ± 10 nm, delivering 15.6

Summary of Immunomodulatory effects of photobiomodulation

(Al Balah et al., 2025) PMC

Background & Rationale

• Photobiomodulation (PBM), also known as low‑level light therapy (LLLT), involves exposure of tissues to red or near‑infrared light to stimulate cellular processes such as mitochondrial activity, ATP production, and downstream signaling pathways. PMC

• The article reviews how PBM influences immune system function by interacting with immune cell populations, inflammation‑mediated pathways, and tissue repair mechanisms. PMC

Key Findings

• The review demonstrates that PBM can modulate immune responses—both innate and adaptive—by affecting immune cell metabolism, cytokine production, and oxidative stress levels. PMC

• PBM has been shown to have anti‑inflammatory effects, promote tissue healing and regeneration, and potentially help manage immune‑related or chronic inflammatory conditions. PMC

• The authors highlight that PBM parameters (wavelength, dose, duration, frequency) are critical

Extended Summary of “The Mechanisms and Efficacy of Photobiomodulation Therapy for Arthritis: A Comprehensive Review”

Zhang, R. & Qu, J. (2023)
(Published in the International Journal of Molecular Sciences, Vol. 24, Issue 18, Article 14293 — PMCID: PMC10531845)

Overview

This comprehensive review explores how Photobiomodulation (PBM) therapy—also known as low-level light therapy—can serve as a non-invasive and promising treatment for arthritis, a chronic condition that affects millions worldwide. PBM involves using red and near-infrared light to stimulate cellular activity, reduce inflammation, and promote tissue repair without the use of drugs or surgery.

The authors, Zhang and Qu (2023), examined a broad range of preclinical and clinical studies to assess both the mechanisms of action and therapeutic efficacy of PBM for arthritis. The review focused on two major types of arthritis: osteoarthritis (OA) and rheumatoid arthritis (RA).

Mechanisms of Action

The paper explains that PBM works

Treating Psoriasis with UVB Light Therapy

UVB (ultraviolet B) light therapy is a common treatment for psoriasis, a chronic skin condition characterized by the rapid growth of skin cells, leading to red, scaly plaques. UVB light therapy involves exposing the affected skin to controlled doses of UVB light. Here's a quick overview of the process:

1. Consultation: Patients should consult a dermatologist to determine if UVB therapy is suitable for their specific type and severity of psoriasis.

2. Treatment Setup: UVB therapy is typically administered in a specialized dermatologist's office or clinic. The patient's skin is exposed to UVB light, either in a full-body chamber or through a handheld UVB device.

3. Frequency: The frequency and duration of treatment sessions vary based on the patient's condition. Initially, treatments may be brief to prevent burning, gradually increasing as the skin adapts.

4. Protection: The therapist or nurse will shield sensitive areas, such as the eyes and genitals,

UVB light treatment triggers the production of vitamin D, which is essential for healthy bones and immune system function. It also promotes the growth of new skin cells and reduces inflammation, leading to improvements in conditions such as psoriasis, eczema, and vitiligo. The treatment is usually administered in a medical setting using specialized equipment, and the dosage of UVB radiation is carefully monitored to minimize the risk of side effects such as sunburn or an increased risk of skin cancer. UVB light treatment can be used as a standalone therapy or in combination with other treatments, depending on the specific condition being treated. While the long-term effects of UVB light treatment are still being studied, current evidence suggests that it can be a safe and effective option for managing certain skin disorders.

Psoriasis

Psoriasis is an inflammatory, non-contagious skin disease that sometimes begins in childhood and adolescence, but usually in adulthood, and is usually lifelong. After allergic contact dermatitis and neurodermatitis, it is one of the most common chronic skin diseases.

The typical appearance is sharply defined, scaly reddening of the skin, which occurs primarily on the elbows, the sides of the knees and the hairy head, and is sometimes itchy. This is also indicated by the medical name of the disease, which comes from the Greek "psao" (I scratch). In addition to the skin, psoriasis also affects the joints in 5-10% of sufferers and the nails in about 50%.

Distribution

The exact number of people currently suffering from psoriasis (prevalence) can only be estimated, as sufficiently large population-based studies are not available. In principle, psoriasis can occur at any age, but studies allow us to distinguish between two types. In the early type, the so-called type 1, to which about

An Update on Narrowband Ultraviolet B Therapy for the Treatment of Skin Diseases

Abstract

High-Throughput RNA Sequencing Reveals the Effect of NB-UVB Phototherapy on Major Inflammatory Molecules of Lesional Psoriasis

https://pubmed.ncbi.nlm.nih.gov/34858799/

Combination of carboxytherapy with NB-UVB leads to higher percentage of repigmentation and patients' satisfaction compared to monotherapy with NB-UVB.

Carboxytherapy has been used in the treatment of autoimmune skin diseases such as psoriasis and morphea. Carboxytherapy has antioxidant effects, and leads to better tissue oxygenation, and release of growth factors. In this article, we decided to evaluate efficacy of combined carboxytherapy and narrowband-ultraviolet B (NB-UVB) compared to NB-UVB alone in the treatment of vitiligo. This is a prospective, split-body double-blind comparative study performed in patients with generalized stable vitiligo in acral areas and extremities referred to dermatology clinic of Afzalipour hospital in Kerman University of Medical Sciences. NB-UVB was performed three times a week in non-consecutive days for 4 months. In each patient, one lesion was randomly treated with carboxytherapy (weekly sessions for total of 16 sessions). Efficacy of treatment was evaluated